People
Faculty and Staff
WANG Jing
Title: Associate Prof.
Research Field: Marine Pharmacology
Department: Key Laboratory of Experimental Marine Biology
Tel/Fax: 0532-82898703
E-mail: jingwang@qdio.ac.cn
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Education
2005-2010 M.S. and Ph.D., majoring in Marine Drug, University of Chinese Academy of Sci.
2001-2005, B.S., majoring in Chemistry, Inner Mongolia University, Hohhot , China

 

Professional Memberships
2013-present, Associate Professor, Institute of Oceanology, Chinese Academy of Sci.
2016-2017, Visiting Scholar, University of California, Davis
2010-2013, Assistant professor, Institute of Oceanology, Chinese Academy of Sci.

 

Research Interests
1. Isolation and identification of bioactive agents from natural products.
2. Understand the chemistry and activity of carbohydrate (such as fucoidan, sulfated polysaccharides).
3. Comprehensive utilization of seaweed resources.

 

Academic Achievements
Engaged in Marine drugs and high value of exploitation and utilization of algae resources, has published 50 SCI articles and applied 26 patents. The mainly research results: 1) Established an ocean acidic polysaccharides/oligosaccharides library. 2) Expand the Marine acidic polysaccharides/oligosaccharide in Parkinson disease. The work won the second prize of the Marine science and technology in 2019.3) Conquer the key technology of high value utilization of algae resource, some achievements transformed in the enterprise successful.

 

Honors and Awards
2019, Second prize of the Marine science and technology
2016, Member, Youth Innovation Promotion Association of Chinese Academy of Sciences
2015, Outstanding Young Technological Talents of Shenyang Branch of Chinese Academy of Sciences

 

Main publications
1. Wang, J., L. Geng, Y. Yue, and Q. Zhang, Use of fucoidan to treat renal diseases: A review of 15 years of clinic studies, in Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics, Pt B, L. Zhang, Editor. 2019. p. 95-111.
2. Liu, Y.J., L.H. Geng, J.J. Zhang, J. Wang*, Q. Zhang, D.L. Duan, and Q.B. Zhang, Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway. Marine Drugs, 2018. 16(3). (*corresponding author)
3. Liu, H.D., J. Wang*, Q.B. Zhang, and H. Zhang, The effect of different substitute groups and molecular weights of fucoidan on neuroprotective and anticomplement activity. International Journal of Biological Macromolecules, 2018. 113: p. 82-89. (*corresponding author)
4. Wang, J., H.D. Liu, X. Zhang, X.P. Li, L.H. Geng, H. Zhang, and Q.B. Zhang, Sulfated Hetero-Polysaccharides Protect SH-SY5Y Cells from H2O2-Induced Apoptosis by Affecting the PI3K/Akt Signaling Pathway. Marine Drugs, 2017. 15(4).
5. Wang, J., Y. Hou, D.L. Duan, and Q.B. Zhang, The Structure and Nephroprotective Activity of Oligo-Porphyran on Glycerol-Induced Acute Renal Failure in Rats. Marine Drugs, 2017. 15(5).
6. Li, X.P. #, J. Wang#, H. Zhang, and Q.B. Zhang, Renoprotective effect of low-molecular-weight sulfated polysaccharide from the seaweed Laminaria japonica on glycerol-induced acute kidney injury in rats. International Journal of Biological Macromolecules, 2017. 95: p. 132-137. (#co-first author)
7. Wang, J., H.D. Liu, W.H. Jin, H. Zhang, and Q.B. Zhang, Structure-activity relationship of sulfated hetero/galactofucan polysaccharides on dopaminergic neuron. International Journal of Biological Macromolecules, 2016. 82: p. 878-883.
8. Wang, J., H.D. Liu, N. Li, Q.B. Zhang, and H. Zhang, The Protective Effect of Fucoidan in Rats with Streptozotocin-Induced Diabetic Nephropathy. Marine Drugs, 2014. 12(6): p. 3292-3306.
9. Wang, J., W.H. Jin, W.J. Zhang, Y. Hou, H. Zhang, and Q.B. Zhang, Hypoglycemic property of acidic polysaccharide extracted from Saccharina japonica and its potential mechanism. Carbohydrate Polymers, 2013. 95(1): p. 143-147.
10. Wang, J., W.H. Jin, Y. Hou, X.Z. Niu, H. Zhang, and Q.B. Zhang, Chemical composition and moisture-absorption/retention ability of polysaccharides extracted from five algae. International Journal of Biological Macromolecules, 2013. 57: p. 26-29.
11. Wang, J., F. Wang, H. Yun, H. Zhang, and Q.B. Zhang, Effect and mechanism of fucoidan derivatives from Laminaria japonica in experimental adenine-induced chronic kidney disease. Journal of Ethnopharmacology, 2012. 139(3): p. 807-813.
12. Wang, J., Q.B. Zhang, Z.S. Zhang, Y. Hou, and H. Zhang, In-vitro anticoagulant activity of fucoidan derivatives from brown seaweed Laminaria japonica. Chinese Journal of Oceanology and Limnology, 2011. 29(3): p. 679-685.
13. Wang, J., Q.B. Zhang, W.H. Jin, X.Z. Niu, and H. Zhang, Effects and mechanism of low molecular weight fucoidan in mitigating the peroxidative and renal damage induced by adenine. Carbohydrate Polymers, 2011. 84(1): p. 417-423.
14. Wang, J., Q.B. Zhang, Z.S. Zhang, H. Zhang, and X.Z. Niu, Structural studies on a novel fucogalactan sulfate extracted from the brown seaweed Laminaria japonica. International Journal of Biological Macromolecules, 2010. 47(2): p. 126-131.
15. Wang, J., Q.B. Zhang, Z.S. Zhang, H.F. Song, and P.C. Li, Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica. International Journal of Biological Macromolecules, 2010. 46(1): p. 6-12.
16. Wang, J., Q.B. Zhang, Z.S. Zhang, J.J. Zhang, and P.C. Li, Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro. International Journal of Biological Macromolecules, 2009. 44(2): p. 170-174.
17. Wang, J., F. Wang, Q.B. Zhang, Z.S. Zhang, X.L. Shi, and P.C. Li, Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro. International Journal of Biological Macromolecules, 2009. 44(5): p. 379-384.
18. Wang, J., L. Liu, Q.B. Zhang, Z.S. Zhang, H.M. Qi, and P.C. Li, Synthesized oversulphated, acetylated and benzoylated derivatives of fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro. Food Chemistry, 2009. 114(4): p. 1285-1290.
19. Wang, J., Q.B. Zhang, Z.S. Zhang, and Z. Li, Antioxidant activity of sulfated polysaccharide fractions extracted from Laminaria japonica. International Journal of Biological Macromolecules, 2008. 42(2): p. 127-132.

 

Patent
1. JingWang, Quanbin Zhang, Hong Zhang, Jin Weihua, Xizhen Niu, Application of a low-viscosity alginate, 2019, Patent No. ZL201610575189.6, China.
2. JingWang, Quanbin Zhang, Hong Zhang, Xizhen Niu, Application of highly sulfated seaweed polysaccharide in repairing facial mask after sun exposure, 2019, Patent No. ZL201610575483.7, China.
3. JingWang, Quanbin Zhang, Hong Zhang, Xizhen Niu, Application of a polysaccharide extracted from Bryopsis plumose. 2015, Patent No. ZL 201310663943.8, China.
4. Quanbin Zhang, JingWang, Hong Zhang, Xizhen Niu, Application of a polysaccharide extracted from Codium fragile (Suringar)Hariot. 2015, Patent No. ZL 201310661898.2, China.
5. Quanbin Zhang, Jingwang, Zhongshan Zhang, Houfang Song, Hong Zhang, Xizhen Niu, Zhien Li, The separation and purification Method of fucogalacan sulfate and its application. 2013, Patent No. ZL 201010157935.2, China.
6. Quanbin Zhang, Wenjing Zhang, JingWang, Jin Weihua, Application of polysaccharide from Asterias rollestoni  Bell,2015,Patent No. ZL 201310010387.4, China.
7. Quanbin Zhang, Yun Hou, JingWang, Wenjing Zhang, Jin Weihua, Hong Zhang, Xizhen Niu, Application of seaweed polysaccharides in preparation of drugs for treating kidney diseases or preventive health products 2014,Patent No. ZL201110211132.5, China.
8. Quanbin Zhang, Jin Weihua, JingWang, Hong Zhang, Xizhen Niu, The application of glucuronic acid-rich low-sulfurized heteroglycan derived from brown algae in the preparation of drugs and health products for the treatment of Parkinson's disease, 2016,Patent No. ZL 201210241647.4, China.
9. Quanbin Zhang, Jin Weihua, JingWang, Lihua Geng, Wenjing Zhang, The application of mannglucuronic acid oligosaccharides and derivatives in the preparation of drugs for treating or preventing kidney disease and / or health products, 2018,Patent No.ZL201510648272.7, China.
10. Quanbin Zhang, Yun Hou, JingWang, Wenjing Zhang, Jin Weihua, Hong Zhang, Xizhen Niu, The use of laver oligosaccharides in the induction of disease resistance of laver, 2015,Patent No. ZL201110440473.X, China.