Name: Mofei Li
Title：Associate professor
Research Field: Pathogenic mechanism and prevention strategy of pathogenic microorganisms
Tel/Fax: +86 0532 82898779
E-mail: limofei@qdio.ac.cn
Resume:
2018.1-present: Associate professor, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.
2018.11-2019.6: Visiting scholar, School of Medicine, University of Maryland, Baltimore, America.
2015.7-2017.12: Assistant professor, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China.
Education：
2012.9- 2015.6: Institute of Oceanology, Chinese Academy of Sciences, Ph.D of Science, marine biology
2009.9- 2012.3: College of Life Science, Ningbo University, Master of Science, marine biology
2005.9-2009.7: College of Chemistry and Life Science, Tianjin Normal University, Bachelor of Science, chemistry and biology
Research Interests:
Pathogenic microorganisms, Fish immunology
Honors and Awards:
The Young scientific and technological talents award, Shenyang college, Chinese Academy of Sciences. 2018.
The Youth Innovation Promotion Association, Chinese Academy of Sciences. 2017.
The Huiquan Young Scholar of Institute of Oceanology, Chinese Academy of Sciences. 2017.
The excellent doctor degree dissertation, Chinese Academy of Sciences. 2016.
The excellence award of President, Chinese Academy of Sciences. 2015.
Selected Publications:
[1] Li MF, Sun L. Edwardsiella tarda Sip2: A serum-induced protein that is essential to serum survival, acid resistance, intracellular replication, and host infection. Frontiers in Microbiology. 2018 9:1084.
[2] Li MF, Sun L. Characterization of a teleost membrane-associated protein that is involved in the regulation of complement activation and bacterial infection. Developmental and Comparative Immunology 2018 79:142-149.
[3] Li MF, Sui ZH, Sun L. A teleost CD46 is involved in the regulation of complement activation and pathogen infection. Scientific Reports 2017 7: 15028.
[4] Li MF, Li J, Sun L. CsMAP34, a teleost MAP with dual role: A promoter of MASP-assisted complement activation and a regulator of immune cell activity. Scientific Reports 2016 6:39287.
[5] Li MF, Hu YH. C5a of Cynoglossus semilaevis has anaphylatoxin-like properties and promotes antibacterial and antiviral defense. Developmental and Comparative Immunology 2016 60:139-148.
[6] Li MF, Zhang J. CsTNF1, a teleost tumor necrosis factor that promotes antibacterial and antiviral immune defense in a manner that depends on the conserved receptor binding site. Developmental and Comparative Immunology 2016 55:65-75.
[7] Li MF, Li YX, Sun L. CD83 is required for the induction of protective immunity by a DNA vaccine in a teleost model. Developmental and Comparative Immunology 2015 51:141-147.
[8] Li MF, Sun L, Jun Li. Edwardsiella tarda evades serum killing by preventing complement activation via the alternative pathway. Fish & Shellfish Immunology 2015 43:325-329. 10
[9] Li MF, Chong Wang, Li Sun. Edwardsiella tarda MliC, a lysozyme inhibitor that participates in pathogenesis in a manner that parallels ivy. Infection and Immunity 2015 83:583-590.
[10] Li MF, Zhang BC, Li J, Sun L. Sil: A Streptococcus iniae bacteriocin with dual role as an antimicrobial and an immunomodulator that inhibits innate immune response and promotes S. iniae infection. PloS One 2014 9:e96222.
[11] Zhang M*, Li MF*, Sun L. NKLP27: A teleost NK-lysin peptide that modulates immune response, induces degradation of bacterial DNA, and inhibits bacterial and viral infection. PloS One 2014 9:e106543.
[12] Li MF, Chen C, Li J, Sun L. The C-reactive protein of tongue sole Cynoglossus semilaevis is an acute phase protein that interacts with bacterial pathogens and stimulates the antibacterial activity of peripheral blood leukocytes. Fish & Shellfish Immunology 2013 34:623-631.
[13] Li MF, Sun BG, Xiao ZZ, Sun L. First characterization of a teleost Epstein-Barr virus-induced gene 3(EBI3) reveals a regulatory effect of EBI3 on the innate immune response of peripheral blood leukocytes. Developmental and Comparative Immunology 2013 41:514–522.
[14] Li MF, Chen C, Sun BG, Sun L. CsTrx80, a truncated form of thioredoxin, possesses chemokine-like property and enhances the immune defense of Cynoglossus semilaevis against bacterial infection. Fish & Shellfish Immunology 2013 35:2026-2031.
[15] Li MF, Hu YH, Zheng WJ, Sun BG, Wang CL, Sun L. Inv1: An Edwardsiella tarda invasin and a protective immunogen that is required for host infection. Fish & Shellfish Immunology 2012 32:586–592.
[16] Li MF, Wang CL, Sun L. A peptidoglycan recognition protein from Sciaenops ocellatus is a zinc amidase and a bactericide with a substrate range limited to Gram-positive bacteria. Fish & Shellfish Immunology 2012 32:322–330.
[17] Li MF, Wang CL, Sun L. A pathogenic Vibrio harveyi lineage causes recurrent disease outbreaks in cultured Japanese flounder (Paralichthys olivaceus) and induces apoptosis in host cells. Aquaculture, 2011 319:30–36.
[18] Hao LX, Li MF#. Molecular characterization and expression analysis of nine CC chemokines in half-smooth tongue sole, Cynoglossus semilaevis. Fish & Shellfish Immunology 2015 47:717-724.
[19] Zhang J, Li MF#. ORF75 of megalocytivirus RBIV-C1: A global transcription regulator and an effective vaccine candidate. Fish & Shellfish Immunology 2015 45:486-494.
[20] Wang MQ, Chi H, Li MF#. A CCL21 chemokine of tongue sole (Cynoglossus semilaevis) promotes host resistance against bacterial infection. Fish & Shellfish Immunology 2015 47:461-469.
[21] Zhang J, Yu LP, Li MF, Sun L. Turbot (Scophthalmus maximus) hepcidin-1 and hepcidin-2 possess antimicrobial activity and promote resistance against bacterial and viral infection. Fish & Shellfish Immunology 2014 38:127-134.
[22] Sui ZH, Li MF, Sun L. Tongue sole (Cynoglossus semilaevis) CD59: A complement inhibitor that binds bacterial cells and promotes bacterial escape from the killing of fish serum. Fish & Shellfish Immunology 2016 58:442-448.