NInstitute of Oceanology,Chinese Academy of Sciences
LI ShiHao


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Name: Shihao Li
Title: Associate Professor
Research Field: Marine Biology
Tel/Fax: +86-532-82898571
2012-present, Assistant Professor, Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences
PhD, 2006-2012, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China
Exchange Student, 2010-2011, Ghent University, Gent, Belgium
B.S., 2002-2006, Ocean University of China, Qingdao, China
Research Interests:
Sex Determination/Differentiation & Sexual Development of Shrimp
Endocrine Regulation on Shrimp Sex, Reproduction and Molting
Active Protein/Polypeptides from Shrimp and Their Application
Study on Functional Genes of Shrimp
Selected Publications:
1) Shihao Li, Fuhua Li*, Bing Wang, Yusu Xie, Rong Wen, Jianhai Xiang*. Cloning and expression profiles of two isoforms of a CHH-like gene specifically expressed in male Chinese shrimp, Fenneropenaeus chinensis. General and Comparative Endocrinology, 167:308-316, 2010.
2) Shihao Li, Fuhua Li*, Zheng Sun, Jianhai Xiang. Two spliced variants of insulin-like androgenic gland hormone gene in the Chinese shrimp, Fenneropenaeus chinensis. General and Comparative Endocrinology, 177:246-255, 2012.
3) Shihao Li, Fuhua Li*, Rong Wen, Jianhai Xiang. Identification and characterization of the sex-determiner transformer-2 homologue in Chinese shrimp, Fenneropenaeus chinensis. Sexual Development, 6:267-278, 2012.
4) Shihao Li, Xiaojun Zhang, Zheng Sun, Fuhua Li*, Jianhai Xiang*. Transcriptome analysis on Chinese shrimp Fenneropenaeus chinensis during WSSV acute infection. PLOS ONE, 8(3): e58627. doi:10.1371/journal.pone.0058627, 2013.
5) Shihao Li, Fuhua Li*, Yusu Xie, Bing Wang, Rong Wen, Chengsong Zhang, Kuijie Yu, Jianhai Xiang. Screening of genes specifically expressed in males of Fenneropenaeus chinensis and their potential as sex markers. Journal of Marine Biology, Volume 2013, Article ID 921067, 9 pages,, 2013.
6) Shihao Li, Shuyue Guo, Fuhua Li*, Jianhai Xiang. Characterization and function analysis of an anti-lipopolysaccharide factor (ALF) from the Chinese shrimp Fenneropenaeus chinensis. Developmental and Comparative Immunology, 46: 349–355, 2014.
7) Shuyue Guo, Shihao Li, Fuhua Li*, Xiaojun Zhang, Jianhai Xiang. Modification of a synthetic LPS-binding domain of anti-lipopolysaccharide factor from shrimp reveals strong structure-activity relationship in their antimicrobial characteristics. Developmental and Comparative Immunology, 45: 227–232, 2014. (Co-first Author)
8) Zheng Sun, Shihao Li, Fuhua Li*, Jianhai Xiang. Bioinformatic prediction of wssv-host protein-protein interaction. BioMed Research International, Volume 2014, Article ID 416543, 9 pages., 2014. (Co-first Author)
9) Shihao Li, Zhiwei Wang, Fuhua Li*, Jianhai Xiang. One type of VEGFR is involved in WSSV infection to the Pacific whiteleg shrimp Litopenaeus vannamei. Developmental and Comparative Immunology, 50:1-8, 2014.
10) Dongdong Wang, Shihao Li, Fuhua Li*. Screening of genes regulated by relish in Chinese shrimp Fenneropenaeus chinensis. Developmental and Comparative Immunology, 41(2):209-216, 2013.
11) Fuhua Li?, Dongdong Wang, Shihao Li, Hui Yana, Jinkang Zhang, Bing Wang, Jiquan Zhang, Jianhai Xiang. A Dorsal homolog (FcDorsal) in the Chinese shrimp Fenneropenaeus chinensis is responsive to both bacteria and WSSV challenge. Developmental and Comparative Immunology, 34(8):874-883, 2010.
12) Dongdong Wang, Fuhua Li*, Shihao Li, Rong Wen, Jianhai Xiang. Expression profiles of antimicrobial peptides (AMPs) and their regulation by Relish. Chinese Journal of Oceanology and Limnology, 30(4): 611-619, 2012.
13) Kartik Baruah*, Parisa Norouzitallab, Li Shihao, Patrick Sorgeloos, Peter Bossier. Feeding truncated heat shock protein 70s protect Artemia franciscana against virulent Vibrio campbellii challenge. Fish and Shellfish Immunology, 34(1):183-191, 2013.
14) Dongdong Wang, Fuhua Li*, Shihao Li, Yanhong Chi, Rong Wen, Ningning Feng , Jianhai Xiang*. An IκB homologue (FcCactus) in Chinese shrimp Fenneropenaeus chinensis. Developmental and Comparative Immunology, 39:352–362, 2013.
15) Rong Wen, Fuhua Li*, Shihao Li, Jianhai Xiang. Function of shrimp STAT during WSSV infection. Fish & Shellfish Immunology, 38: 354e360, 2014.
16) Yusu Xie, Fuhua Li*, Bing Wang, Shihao Li, Dongdong Wang, Hao Jiang, Chengsong Zhang, Kuijie Yu, Jianhai Xiang*. Screening of genes related to ovary development in Chinese shrimp Fenneropenaeus chinensis by suppression subtractive hybridization. Comparative Biochemistry and Physiology, Part D, 5:98–104.
17) Rong Wen, Fuhua Li*, Yusu Xie, Shihao Li, Jianhai Xiang*. A homolog of the cell apoptosis susceptibility gene involved in ovary development of Chinese shrimp Fenneropenaeus chinensis. Biology Reproduction, 86(1):7, 1-7, 2012.
18) Rong Wen, Fuhua Li*, Zheng Sun, Shihao Li, Jianhai Xiang*. Shrimp MyD88 responsive to bacteria and white spot syndrome virus. Fish and Shellfish Immunology, 34(2):574-581, 2013.
19) Rong Wen, Fuhua Li*, Yusu Xie, Shihao Li, Chengsong Zhang, Kuijie Yu, Jianhai Xiang. Cloning and expression analysis on a homolog of spermatogonial stem-cell renewal factor in Fenneropenaeus chinensis. Invertebrate Reproduction & Development, DOI: 10.1080/07924259.2014.905501.
20) Li F, Yan H, Wang D, Priya TA, Li S, Wang B, Zhang J, Xiang J*. Identification of a novel relish homolog in Chinese shrimp Fenneropenaeus chinensis and its function in regulating the transcription of antimicrobial peptides. Developmental and Comparative Immunology, 33(10):1093-1101, 2009.
21) Yanhong Chi, Fuhua Li*, Yumiao Sun, Rong Wen, Shihao Li. Expression and function analysis of Rac1 homolog in Chinese shrimp Fenneropenaeus chinensis. Fish and Shellfish Immunology, pii: S1050-4648(13)00644-X. doi: 10.1016/j.fsi.2013.07.006, 2013.
22) Sun Y, Li F, Sun Z, Zhang X, Li S, Zhang C, Xiang J*. (2014) Transcriptome Analysis of the Initial Stage of Acute WSSV Infection Caused by Temperature Change. PLoS ONE 9(3): e90732. doi:10.1371/journal.pone.0090732.
23) Jinkang Zhang, Fuhua Li*, Hao Jiang, Yang Yu, Chengzhang Liu, Shihao Li, Bing Wang, Jianhai Xiang. Proteomic analysis of differentially expressed proteins in lymphoid organ of Fenneropenaeus chinensis response to Vibrio anguillarum stimulation. Fish and Shellfish Immunology, 29:186-194, 2010.
24) Fuhua Li, Wei Luan, Chengsong Zhang, Jiquan Zhang, Bing Wang, Yusu Xie, Shihao Li, Jianhai Xiang*. Cloning of cytoplasmic heat shock protein 90 (FcHSP90) from Fenneropenaeus chinensis and its expression response to heat shock and hypoxia. Cell Stress and Chaperones, 14:161–172, 2009.
25) Hao Jiang, Fuhua Li, Yusu Xie, Bingxin Huang, Jinkang Zhang, Jiquan Zhang, Chengsong Zhang, Shihao Li, Jianhai Xiang*. Comparative proteomic profiles of the hepatopancreas in Fenneropenaeus chinensis response to hypoxic stress. Proteomics, 9:3353–3367, 2009.

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