NInstitute of Oceanology,Chinese Academy of Sciences


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Name:(姓名) Rui LIU

Title:(职称)Associate Professor

Subject:(专业)Marine microbiology



Address:(通信地址)7 Nanhai Road, Qingdao




2017-, Associate Professor, Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences

2011-2017, Assistant Professor, Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences



Ph.D., 2011, Ocean University of China, Qingdao, China.

B.S. , 2006, Jinan University, Jinan, China.


Professional Memberships:(组织任职)


Research Interests:(研究领域)

Marine microbiology, Environmental microbiology, Isolation and culture of microorganisms, Active substances of microorganisms 


Academic Achievements:(科研成果)


Honors and Awards:(获得荣誉、获奖情况)

First prize in Marine Science and Technology (2017)


Selected Publications:(发表论文、出版书籍)

1. Rui Liu, Rikuan Zheng, Ge Liu, Chaomin Sun. The cyclic lipopeptides suppress the motility of Vibrio alginolyticus via targeting the Na+-driven flagellar motor component MotX. Environmental Microbiology. 2020. DOI: 10.1111/1462-2920.15144.

2. Rui Liu, Qi Cheng, Xiaorui Song, Hao Wang, Xiudan Wang, Lingling Wang, Beiwei Zhu, Linsheng Song. A vital ubiquitin-conjugating enzyme CgUbe2g1 participated in regulation of immune response of Pacific oyster Crassostrea gigas. Developmental and Comparative Immunology, 2019, 91: 132-142.

3. Pengyuan Xiu#, Rui Liu#, Dechao Zhang, Chaomin Sun. Pumilacidin-like lipopeptides derived from marine bacterium Bacillus sp. suppress the motility of Vibrio alginolyticus. Appl Environ Microbiol. 2017. doi:10.1128/AEM.00450-17. (# Co-first author)

4. Rui Liu, Qi Cheng, Xiudan Wang, Hao Chen, Weilin Wang, Huan Zhang, Lingling Wang, Linsheng Song. The B-cell translocation gene 1 (CgBTG1) identified in oyster Crassostrea gigas exhibit multiple functions in immune response. Fish Shellfish Immunol. 2017; 61: 68-78.

5. Rui Liu, Limei Qiu, Qi Cheng, Huan Zhang1, Lingling Wang, LinshengSong. Evidence for cleavage of the metalloprotease Vsm from Vibrio splendidus strain JZ6 by an M20 peptidase (PepT-like Protein) at low temperature. Front Microbiol. 2016; 7: 1684.

6. Rui Liu, Hao Chen, Ran Zhang, Zhi Zhou, Zhanhui Hou, Dahai Gao, Huan Zhang, Lingling Wang, Linsheng Song. Comparative transcriptome analysis of Vibrio splendidus JZ6 reveals the mechanism of its pathogenicity at low temperatures. Appl Environ Microbiol. 2016; 7: 2050-2061.

7. Ran Zhang#, Rui Liu#, Lusheng Xin, Hao Chen, Chenghua Li, Lingling Wang, Linsheng Song. A CgIFNLP receptor from Crassostrea gigas and its activation of the related genes in human JAK/STAT signaling pathway. Dev Comp Immunol. 2016; 65: 98-106. (# Co-first author)

8. Rui Liu, Limei Qiu, Xin Zhao, Huan Zhang, Lingling Wang, Zhanhui Hou, Dahai Gao, Linsheng Song. Variation analysis of pathogenic Vibrio spp. and Pseudomonas spp. in Changhai mollusc farming waters using real-time PCR assay during 2011-2014. Marine Biology Research. 2016; 12: 146-157.

9. Rui Liu, Lingling Wang, Ying Sun, Leilei Wang, Huan Zhang, Linsheng Song. A low-density lipoprotein receptor-related protein (LRP)-like molecule identified from Chlamys farreri participated in immune response against bacterial infection. Fish Shellfish Immunol. 2014; 36(2): 336-343.

10. Rui Liu, Limei Qiu, Zuoan Yu, Jun Zi, Feng Yue, Lingling Wang, Huan Zhang, Weiming Teng, Xiangfeng Liu, Linsheng Song. Identification and characterisation of pathogenic Vibrio splendidus from Yesso scallop (Patinopecten yessoensis) cultured in a low temperature environment. J Invertebr Pathol. 2013; 114(2): 144-150.

11. Rui Liu, Jixiang Chen, Kesheng Li, Xiaohua Zhang. Identification and evaluation as a DNA vaccine candidate of a virulence-associated serine protease from a pathogenic Vibrio parahaemolyticus isolate. Fish Shellfish Immunol. 2011; 30: 1241-1248.

12. Jing Zhang, Rui Liu, Shichuan Xi, Ruining Cai, Xin Zhang, Chaomin Sun. A novel      bacterial thiosulfate oxidation pathway provides a new clue about the formation of zero-valent sulfur in deep sea. ISME J. 2020 . DOI: 10.1038/s41396-020-0684-5.

13. Zhongxiu Liang, Rui Liu, Depeng Zhao, Lingling Wang, Mingzhe Sun, Mengqiang Wang, Linsheng Song*, Ammonia exposure induces oxidative stress, endoplasmic reticulum stress and apoptosis in hepatopancreas of pacific white shrimp (Litopenaeus vannamei). Fish Shellfish Immunol. 2016, 54: 523-528.

14. Ran Zhang, Rui Liu, Weilin Wang, Lusheng Xin, Lingling Wang, Chenghua Li, and Linsheng Song*, Identification and Functional Analysis of a Novel IFN-like Protein (CgIFNLP) in Crassostrea gigas, Fish Shellfish Immunol. 2015, 44(2): 547-554.

15. Weilin Wang, Rui Liu, Tao Zhang, Ran Zhang, Xiaorui Song, Lingling Wang, Linsheng Song. A novel phagocytic receptor (CgNimC) from Pacific oyster Crassostrea gigas with lipopolysaccharide and gram-negative bacteria binding activity. Fish Shellfish Immunol. 2014; 43(1):103-110.

16. Ge Liu, Kai Wang, Shan Kuang, Ruobing Cao, Li Bao, Rui Liu, HongWei Liu, Chaomin Sun. The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death. Cell Death and Disease, 2018, 9(689). Doi: 10.1038/s41419-018-0731-6.

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