NInstitute of Oceanology,Chinese Academy of Sciences
MA QingJun


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Name:(姓名)Qingjun Ma
Research Field:(研究领域) Marine Biology, Structural Biology

2015 – present, professor, Institute of Oceanology, Chinese Academy of Sciences
2011 – 2014, group leader, Institute for Biochemistry, University of Luebeck, Germany
2009 – 2010, scientist, Institute for Crystallography, Free University of Berlin, Germany
2008, scientist, Max-Planck Research Unit for Structural Molecular Biology, Germany
2004 – 2007, postdoc, EMBL Hamburg outstation

2003 Dr. rer. nat., University of Goettingen, Germany
2000 M.S. of Molecular Biology, Institute of Biophysics, Chinese Academy of Sciences
1997 B.S. of Microbiology, Nankai University, China

Professional Memberships:(组织任职)

Research Interests:(研究方向)
1. Structural and functional study of proteins related to marine diseases;
Structure-based drug and vaccine design.
2. Enzyme discovery and engineering for bioresource utilization.

Honors and Awards:(获得荣誉、获奖情况)
2015, “One Hundred Talent Program” award, CAS

Selected Publications:(发表论文、专利、出版书籍等)
? Qingjun Ma, Yusuf Akhter, Matthias Wilmanns, and Matthias T. Ehebauer. Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase from Mycobacterium tuberculosis. Protein Science, 23, 932-939 (2014).
? Yibei Xiao#, Qingjun Ma#, Tobias Restle, Weifeng Shang, Dmitri I. Svergun, Rajesh Ponnusamy, Georg Sczakiel, Rolf Hilgenfeld. Non-structural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer that Exhibits Primer-independent RNA Polymerase Activity. J Virol, 86, 4444-4454 (2012). (#共同第一作者)
? Yijian Rao#, Qingjun Ma#, Ardeschir Vahedi-Faridi, Anna Sundborger, Arndt Pechstein, Dmytro Puchkov, Lin Luo,Oleg Shupliakov, Wolfram Saenger, Volker Haucke. Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation. P Natl Acad Sci USA, 107, 8213-8218(2010). (#共同第一作者)
? Qingjun Ma, Xin Zhao, Ali Nasser Eddine, Arie Geerlof, Xinping Li, John E. Cronan, Stefan H. E. Kaufmann, Matthias Wilmanns. The Mycobacterium tuberculosis LipB enzyme functions as a cysteine/lysine dyad acyltransferase. P Natl Acad Sci USA, 103, 8662-8667 (2006).
? Qingjun Ma#, Chaoshe Guo#, Kathrin Barnewitz, George M. Sheldrick, Hans-Dieter Soeling, Isabel Uson, David M. Ferrari. Crystal structure and function analysis of Drosophila Wind – a PDI-related protein. J Biol Chem, 278, 44600-44607(2003). (#共同第一作者)
? Qing-jun Ma, Jian-hui Li, Hui-guang Li, Shen Wu, Yi-cheng Dong. Crystal structure of beta-luffin, a ribosome inactivating protein at 2.0? resolution. Acta Crystallogr D, 59, 1366-1370 (2003).
? Qing-jun Ma, Guang Yao, Shen Wu, Hui-guang Li, Jian-hui Li, Yi-cheng Dong. Crystallization and preliminary X-ray analysis of luffaculin, a ribosome-inactivating protein from sponge-gourd seeds. Acta Crystallogr D, 56, 185-186 (2000).

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