NInstitute of Oceanology,Chinese Academy of Sciences
People
ZHANG LinLin

2019-07-19

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Name:(姓名):Linlin Zhang

Title:(职称)Professor

Subject:(专业)

EvoDevoGenomics; Marine Adaptation; Aquaculture Resource Development

Tel/Fax:(电话/传真)86-532-82896651

E-mail:(电邮)linlinzhang@qdio.ac.cn

Address:(通信地址)7 Nanhai Road, Qingdao, China

More:(其它如职务、所属实验室、个人网站链接等)

Experimental Marine Biological Laboratory

https://scholar.google.com/citations?user=yle84SMAAAAJ&hl=en

 

Resume:(个人简历,总结性叙述)

I have been trained as evolutionary biologist with emphasis on molecular genetics and genomics skills. My graduate study with Dr. Guofan Zhang at Chinese Academy of Sciences focused on using comparative genomics, transcriptomics and molecular biology techniques to study stress response adaptation in oysters. During my postdoc training with Dr. Robert Reed in Cornell University, I have developed efficient CRISPR/Cas9 genome editing in butterflies and used CRISPR to study developmental genetics basis of butterfly color pattern evolution. I have also applied epigenomics techniques to study cis-regulatory evolution in butterflies. I then continued my journey in Evo-Devo field and shift my focus back to marine organisms. I did second postdoc with Dr. Elaine Seaver at University of Florida Whitney lab studying regeneration in Annelid. I am now a principal investigator in Institute of Oceanology, Chinese Academy of Sciences. My lab is engaged in research at the intersection of biological oceanography and EvoDevo. We combine field (marine), laboratory and computational studies to investigate the evolution, ecology, function of marine biodiversity and are motivated by basic research questions related to marine adaptation.

 

Professional Appointments:

2019-present, Principal Investigator, Institute of Oceanology, CAS

2017-2018,  Postdoc, University of Florida, The Whitney laboratory

2014-2017,  Postdoc, Cornell University, Department of Ecology and Evolutional Biology

2012-2013,  Assistant Research Associate, Institute of Oceanology, CAS

 

Education:(教育经历)

2007- 2012,  Ph.D. Institute of Oceanology, Chinese Academy of Sciences 

2003- 2007,  B.Sc. Ocean University of China

 

Professional Memberships:(组织任职)

Council Member, Chinese Society of Molluscs

 

Research Interests:(研究领域)

EvoDevo; Marine biodiversity; Comparative Functional genomics; Genome editing; Gene regulation; Adaptive evolution; Aquaculture Resource Development;

 

Academic Achievements:(科研成果)

 

 

Honors and Awards:(获得荣誉、获奖情况)

Fusui Zhang Molluscan Award for young scholar, 2019

Second Prize of Shandong Province Science and Technology Progress, 4/5, 2017 

Cozzarelli Prize, 2017 (one of the six papers published on PNAS, 2017)

 

Selected Publications:(发表论文、出版书籍)

1.  Zhang, L., Mazo-Vargas, A. & Reed R.* (2017). A single master regulatory gene coordinates the evolution and development of butterfly color and iridescence. Proceedings of the National Academy of the USA, 114(40):10707-12. PNAS (Cover Story)

Media coverage: New York Times, Nature, The atlantic, The Washington Post

2.  Zhang, L.*, Martin, A., Perry, M., van der Burg, K., Matsuoka, Y., Monteiro A.* & Reed R.* (2017). Genetic Basis of melanin pigmentation in butterfly wings. Genetics, 205(4):1537-1550.  (Cover story)

3. Huang, B.#, Zhang, L.#, Du, Y., Xu, F., Li, L.* & Zhang, G.* (2017). Characterization of the mollusc RIG-I/MAVS pathway reveals an archaic antiviral signaling framework in invertebrates. Scientific reports, 7:8217.  (# co-first author) 

4. Zhang, L. & Reed R.D.* (2016). Genome editing in butterflies reveals that spalt promotes and Distal-less represses eyespot colour patterns. Nature Communications, 7, 11769. Ncomms

Media coverage: Science News, Science Daily, EurkAlt, Newswise, Technology.org, Health Medicinet, Cornell Chronicle, Gazeta.ru, NU

5.  Huang, B.#, Zhang, L.#, Tang, X., Zhang, G., & Li, L.* (2016). Genome-wide analysis of alternative splicing provides insights into stress adaptation of the Pacific oyster. Marine Biotechnology, 18(5):598-609.  (# co-first author)

6. Zhang, L., Li, L., Guo, X.*, Litman, G. W.*, Dishaw, L. J., & Zhang, G.* (2015). Massive expansion and functional divergence of innate immune genes in a protostome. Scientific Reports, 5, 8693. PubMed 100 topcited, 2015

7. Zhang, L., Li, L., Zhu, Y., Zhang, G.*, & Guo, X* (2014). Transcriptome analysis reveals a rich gene set related to innate immunity in the eastern oyster (Crassostrea virginica). Marine Biotechnology, 16(1),17-33.  

8. Zhang, G. *#, Fang, X. #, Guo, X. #, Li, L. #, Luo, R. #, Xu, F. #, Yang, P. #, Zhang, L. #, Wang, X. #, Qi, H., Xiong, Z., Que, H., Xie, Y., Holland W H, H., Paps, J., Zhu, Y., Wu, F., Chen, Y., Wang, J., Peng, C., Meng, J., Yang, L., Liu, J., Wen, B., Zhang, N., Huang, Z., Zhu, Q., Feng, Y., Mount, A., Hedgecock, D., Zhe, X., Liu, Y., Domazet Loso, T., Du, Y., Sun, X., Zhang, S., Liu, B., Cheng, P., Jiang, X., Li, J., Fan, D., Wang, W., Fu, W., Wang, T., Wang, B., Zhang, J., Peng, Z., Li, Y., Li, N., Wang, J., Cheng, M., He, Y., Tan, F., Song, X., Zheng, Q., Huang, R., Yang, H., Du, X., Chen, L., Yang, M., Gaffney, P.M., Wang, S., Luo, L., She, Z., Ming, Y., Huang, W., Zhang, S., Huang, B., Zhang, Y., Qu, T., Ni, P., Miao, G., Wang, J., Wang, Q.,  Steinberg, C.E.W., Wang, H., Li, N., Qian, L., Zhang, G., Li, Y., Yang, H., Liu, X., Wang., J., Yin, Y.* & Wang, J.*  (2012). The oyster genome reveals stress adaptation and complexity of shell formation. Nature, 490 (7418), 49-54. (# co-first author)  

Media coverage: Washington Post, Science News, BBC News, Science Daily, Scientific American, Fox News, Yahoo News

9. Zhang, L., Li, L. & Zhang, G.* (2011). A Crassostrea gigas Toll-like receptor and comparative analysis of TLR pathway in invertebrates. Fish & Shellfish Immunology, 30, 653-60.  

10.  Zhang, L., Li, L. & Zhang, G.* (2011). Gene discovery, comparative analysis and expression profile reveal the complexity of the Crassostrea gigas apoptosis system. Developmental & Comparative Immunology, 35: 603-610.  

 

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